Abstract: Soybean antigenic proteins represent the primary allergens triggering allergic reactions in animals. Upon ingestion，these proteins compromise the intestinal antioxidant capacity of aquatic species，damage intestinal tissue structure，induce inflammatory response，and impair mucosal barrier function. Consequently，they suppress growth and development in aquatic animals，thereby limiting the application of soybean protein source in compound feeds for aquaculture. This review systematically examines the antinutritional effects of soybean antigenic proteins on aquatic animals and discusses potential mitigation strategies. The findings provide a theoretical support for enhancing the utilization efficiency of soybean protein，optimizing compound formulations，and reducing feed costs in aquatic animal production.

Key words: Soybean antigen protein, Aquatic animals, Anti?nutritional effect, Mitigation measures

摘要： 大豆抗原蛋白是引起动物机体过敏反应的主要致敏原，其进入动物机体后会降低水产动物肠道的抗氧化能力，破坏肠道组织结构，诱发肠道炎症反应，损害肠道黏膜屏障功能，从而抑制水产动物的生长发育，导致大豆蛋白源在水产动物配合饲料中应用受限。该文阐述了大豆抗原蛋白对水产动物的抗营养作用及其消减措施，为提高大豆蛋白源的利用率、优化水产动物配合饲料配方以及降低饲料成本提供理论依据。

关键词: 大豆抗原蛋白, 水产动物, 抗营养作用, 消减措施