Abstract: Ultrasound examination has become a routine examination method in clinical diagnosis and treatment of pets，especially in soft tissues such as liver，spleen，heart and kidney. However，due to the complex structure and special location of the liver，it is difficult to diagnose liver diseases by routine ultrasound examination. The contrast? enhanced ultrasound technology has become an important means for the diagnosis of liver diseases in human medicine， but it is rarely used in veterinary clinics. The contrast?enhanced ultrasound has unique advantages，especially in the diagnosis of liver benign and malignant lesions. In this review，we summarized the principle，theoretical basis， clinical application，and research progress of contrast?enhanced ultrasound in the diagnosis of canine liver tumors ．

Key words: Contrast?enhanced Ultrasound； Contrast Enhancement； Canine； Liver Tumor

摘要： 在宠物临床诊疗中，超声检查已经成为常规检查手段，特别是在肝脏、脾脏、心脏与 肾脏等软组织器官中的应用更有优势；但由于肝脏结构复杂且位置特殊，肝脏常规超声检查对 诊断肝脏疾病有一定难度。超声造影有着独特的优势，尤其是鉴别肝脏良恶性病变和恶性病 变诊断，该技术已成为人类医学肝脏疾病诊断的重要手段，但在兽医临床诊断中的应用较 少。本文介绍超声造影技术的原理、理论基础及其在犬肝脏肿瘤诊断中的临床应用与研究进 展。

关键词: 超声造影； 对比增强； 犬； 肝肿瘤