Abstract: Lumpy skin disease（LSD），also known as bovine nodular rash or bovine lumpy disease，is a highly infectious class II animal disease that poses a serious harm to the growth and production of cattle. Infected cattles had widespread skin nodules with fever，swollen lymph nodes，edema of the limbs and perineum，yellow secretions from the mouth，nose and eyes，and decreased milk production. The etiology，epidemiology，transmission routes，clinical symptoms，pathological changes，diagnosis，treatment and preventive measures is discussed in this article，and we proposed to strengthen the barn feeding management and made disinfection measures to isolate infected area，to carry out the zap insect ?? borne control work and the surrounding environment to reduce or avoid losses，and proposes to strengthen cattle housing management and disinfection measures，isolate the infected area，and carry out insect vector control in cattle farms and the surrounding environment to improve the prevention and control ability and minimize or avoid losses.

Key words: bovine nodular dermatosis； Clinical symptoms； Pathological changes； Diagnosis and prevention

摘要： 牛结节性皮肤病（lumpy skin disease，LSD），又称牛结节疹或牛疙瘩病，是一类具有 高度传染性二类动物疫病，该病对牛群生长发育和生产有严重的危害。感染该病毒的病牛全 身皮肤出现广泛结节，同时伴有发热、体表淋巴结肿大、四肢及会阴部水肿、口鼻及眼部出现黄 色分泌物、母牛的产奶量下降等症状。本文从该病的病原学、流行病学、传播途径、临床症状、 病理变化、诊断和治疗与预防措施等方面进行论述总结，提出加强牛舍饲养管理及消毒措施、 对疫病区进行隔离、开展牛场以及周围环境的虫媒控制工作等，综合提高防控能力，最大程度 上减少或避免损失。

关键词: 牛结节性皮肤病； 临床症状； 病理变化； 诊断与防治