［1］ WAN X L，LI X H，OSMUNDSON T，LI C L，YAN H. Whole?
genome sequence analyses of Glaesserella parasuis isolates
reveals extensive genomic variation and diverse antibiotic
resistance determinants［J］. PeerJ，2020，22（8）：e9293. ［2］ 王乐，赵战勤，薛云，等.副猪嗜血杆菌国内流行血清型菌株
的致病性比较研究［J］. 中国兽医学报，2014，34（11）：1748?
1752. ［3］ MAHMMOD Y S，CORREA FIZ F，ARAGON V. Variations in
association of nasal microbiota with virulent and non ? virulent
strains of Glaesserella （Haemophilus） parasuis in weaning
piglets［J］.Veterinary Research，2020；51（1）：7. ［4］ LI G，NIU H，ZHANG Y H，LI Y L，XIE F，LANGFORD P R，
LIU S G，WANG C L. Haemophilus parasuis cytolethal
distending toxin induces cell cycle arrest and p53 ? dependent
apoptosis［J］.Plos One，2017，12（5）：177?199. ［5］ OLVERA A，BALLESTER M，NOFRARíAS M. Differences in
phagocytosis susceptibility in Haemophilus parasuis strains［J］.
Veterinary Research，2009，40（24）：1?12. ［6］ PATHIRANA RD，KAPARAKIS L M. Bacterial membrane
vesicles：Biogenesis，immune regulation and pathogenesis［J］.
Cellular Microbiology，2016，18（11）：1518?1524. ［7］ LI M，SONG S，YANG D，LI C，LI G. Identification of secreted
proteins as novel antigenic vaccine candidates of Haemophilus
parasuis serovar 5［J］. Vaccine，2015，33（14）：1695?1701. ［8］ ATTIA AS，LAFONTAINE E R，LATIMER J L，et al. The
UspA2 protein of Moraxella catarrhalis is directly involved in the
expression of serum resistance［J］. Infection and immunity，
2005，（73）：2400?2410. ［9］ MARTíNEZ M V，SOLER L P，MOLERES J，GARMENDIA J，
ARAGON V. Distribution of genes involved in sialic acid
utilization in strains of Haemophilus parasuis［J］. Microbiology，
2012；158（8）：2117?2124. ［10］ZHAO L Y，GAO X L，LIU C N，et al. Deletion of the vacJ gene
affects the biology and virulence in Haemophilus parasuis
serovar 5［J］. Gene，2017，603：42?53. ［11］MARTA C，VIRGINIA A S. Serum ? resistance in Haemophilus
parasuis is associated with systemic disease in swine［J］.
Veterinary journal，2008，（175）：384?389. ［12］LICGTENSTEIGER C A，STEEBERGEN S M，LEE R M，et al.
Direct PCR analysis for toxigenic Pasteurella multocida.［J］.
Journal of clinical microbiology，1996，34（12）：035?039. ［14］JANBEN T，SCHWAZ C，PREIKSCHAT P，et al. Virulence ?
associated genes in avian pathogenic Escherichia coli（APEC）
isolated from internal organs of poultry having died from
colibacillosis［J］. International Journal of Medical Microbiology，
2001，291（5）：371?378.
