广东畜牧兽医科技 ›› 2023, Vol. 48 ›› Issue (5): 23-26.DOI: 10.19978/j.cnki.xmsy.2023.05.04

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人兽共患猪δ冠状病毒研究综述:病原学,流行病学 及防控措施

郭怡凡,颜权辉,邢家宝,李子杰,曾伟俊,范双旗*   

  1. (华南农业大学兽医学院,广东 广州 510642)
  • 出版日期:2023-10-20 发布日期:2023-10-18
  • 通讯作者: 范双旗

A Review of Research on Zoonotic Porcine Deltacoronavirus: Etiology, Epidemiology, Prevention and Control

GUO Yifan,YAN Quanhui,XING Jiabao,LI Zijie,ZENG Weijun,FAN Shuangqi**   

  1. (College of Veterinary Medicine,South China Agricultural University,Guangzhou Guangdong 510642)
  • Online:2023-10-20 Published:2023-10-18

摘要: 近年来,人兽共患的冠状病毒(Coronavirus,CoV)感染不断新发或再发,给公共卫生 安全和健康养殖带来巨大威胁。最早报告于香港的猪δ冠状病毒(Porcine deltacoronavirus,PD? CoV)感染就是其中之一,其病原学特征于2014年在美国首次确定,随后北美和亚洲各国也进 行了广泛的报道。PDCoV 表现出高度的遗传多样性,在谱系间和谱系内存在频繁的重组现 象。该病毒可同时感染鸟类和包括人类在内的多种哺乳动物,并且感染人的不同谱系毒株还 具有趋同进化的特性,这也为维护公共卫生安全带来了严峻挑战。本文通过综述人兽共患猪δ 冠状病毒的研究现状,从病原学、流行病学等方面分析其出现的过程和原因,以期进一步了解 猪δ冠状病毒的起源及跨物种传播途径并提出防控建议。

关键词: 猪δ冠状病毒, 病原学, 流行病学, 防控

Abstract: In recent years,zoonotic coronaviruses have been emerging or re ?emerging,posing a great threat to public health and the farming economy. Porcine deltacoronavirus,which was first reported in Hong Kong,is one of them. Its etiological characteristics were first identified in the United States in 2014,followed by extensive reports in various countries in North America and Asia. The virus has shown frequent inter ? lineages and intra ? lineages recombination and high genetic diversity,infecting birds and several mammals,including humans.In addition, different lineages of strains infecting humans also have the characteristics of convergent evolution,which also brings severe challenges to human health. In this paper,we reviewed the research status of zoonotic porcine deltacoronavirus, and analyzed the etiology and epidemiology of porcine deltacoronavirus,so as to further understand the origin and cross?species transmission route of porcine deltacoronavirus,and put forward prevention and control suggestions.

Key words: Porcine deltacoronavirus, Etiology, Epidemiology, Prevention and control

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