Inflammatory bowel disease（IBD）was characterized by persistence and recurrence． The current clinical treatment drugs were ineffective，expensive，and have serious adverse reactions，which causing long ? term distress to patients. Natural polysaccharides have many advantage，such as had a wide range of sources，lower cost， and fewer side effects，which can treat IBD by reducing inflammation，alleviating oxidative stress，adjusting microbial flora，and protecting mucosal barrier. In addition，polysaccharides have been studied as carriers of IBD drugs. However，due to the wide variety and complex structure of polysaccharides，most studies are still in the stage of animal experiments. This current paper mainly discusses the recent research progress of natural polysaccharides in the treatment of IBD，in order to provided more evidences for the further development and utilization of polysaccharides ．