关键词: PK/PD同步模型, 抗菌药物, 给药方案, 细菌耐药性

Abstract: The remarkable progress of veterinary antimicrobial drugs （AMDs） pharmacokinetics/ pharmacodynamics（PK/PD）models has been made in recent years. Understanding the basic concept of PK/PD model and optimizing the dosage regimen can improve the antibacterial effect of AMDs and reduce the occurrence of drug resistance. This paper introduces the research methods and progress of PK/PD model，as well as the challenges and application prospects of PK/PD model in veterinary AMDs and its future development trend，and provide a theoretical basis for the research of PK/PD model for veterinary AMDs.

Key words: Pharmacokinetics/Pharmacodynamics Models, Veterinary Antimicrobial Drugs, Dosage Regimen, Bacterial Resistance