广东畜牧兽医科技 ›› 2022, Vol. 47 ›› Issue (6): 21-25.DOI: 10.19978/j.cnki.xmsy.2022.06.05

• 试验研究 • 上一篇    下一篇

中药复方制剂对实验兔感染犬小孢子菌的疗效试验研究

林仁钊1,许春荣2,植婵萍3,林飞1,陈嘉欣1,苏雅琳1,石达友1**   

  1. (1.华南农业大学兽医学院,广东 广州 510642; 2. 广东原喵智能科技有限公司,广东 顺德 528000; 3.广东茂名农林科技职业学院,广东 茂名 525000)
  • 出版日期:2022-12-22 发布日期:2022-12-22
  • 通讯作者: 石达友
  • 基金资助:
    广东省高校质量工程建设项目?科产教融合实践教学基地(粤教高函〔2021〕29号);企业横向科研项目(一种含中草药的功能性猫 砂的试验研究与开发应用)

Efficacy of a Chinese herbal compound against Microsporum canis infection in rabbits

LIN Renzhao1 ,XU Chunrong2 ,ZHI Chanping3 ,LIN Fei1 ,CHEN Jiaxin1 ,SU Yalin1 ,SHI Dayou1*   

  1. (1.College of Veterinary Medicine,South China Agricultural University,Guangzhou Guangdong 510642; 2. Guangdong Original Meow Intelligent Technology Co Ltd,Shunde Guangdong 528000; 3. Guangdong Maoming Agricultural and Forestry Science and Technology Vocational College, Maoming Guangdong 525000)
  • Online:2022-12-22 Published:2022-12-22

摘要: 为观察中药复方制剂对实验兔感染犬小孢子菌的疗效,构建实验兔犬小孢子菌皮 肤感染模型,分别使用药物进行治疗,并观察相关试验指标。试验设空白对照组(K)、模型对 照组(M)、中药复方治疗组(CM)以及特比萘芬治疗组(T)。试验结果显示,中药复方可显著降 低实验兔感染犬小孢子菌后的皮肤损伤评分(P<0.05),显著减少犬小孢子菌皮肤感染实验兔 创面的犬小孢子菌数量(P<0.05),能明显改善实验兔的临床病变症状与促进组织修复,与特比 萘芬治疗效果相比其综合评价差异不显著。表明中药复方制剂对实验兔感染犬小孢子菌具有 显著的治疗作用,可为宠物临床上使用中西药结合治疗动物皮肤癣菌提供实验数据与理论依 据。

关键词: 皮肤癣菌病, 犬小孢子菌, 中药复方, 特比萘芬,

Abstract: In order to evaluate the efficacy of a Chinese herbal compound on Microsporum canis infection inefficacy yielded a non ? significant difference with terbinafine treatment. This study showed that the Chinese herbal compound had significant therapeutic effects on experimental rabbits infected with Microsporum canis,which can provide experimental data and theoretical basis for the use of a combination of Chinese and Western medicines in the treatment of dermatophytosis in animals in the pet clinic. rabbits,a Microsporum canis infection model of rabbit skin was developed for different treatments. The rabbits were divided into blank control group(K),model control group(M),herbal compound treatment group(CM)and terbinafine treatment group(T). The results showed that the Chinese herbal compound significantly reduced the skin damage score(P<0.05)and significantly reduced the number of Microsporum canis on the skin wounds(P<0.05), significantly improved the clinical symptoms of the rabbits and promoted tissue repair. The combined evaluation of its

Key words: Dermatophytosis, Microsporum canis, Herbal Compound, Terbinafine, Rabbit

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