关键词: 裸花紫珠； 水提工艺； 毛蕊花糖苷； 木犀草苷

Abstract: This study aimed to investigate the effect of water extraction process on the main active components of Cllicarpa nudiflora. An orthogonal experiment was designed to study optimal water extraction technology of Cllicarpa nudiflora based on the investigating the solid??liquid ratio and the number of decoction times on the contents of luteolin and verbascoside. The results showed that there was no significant difference in the effect of solid ?liquid ratio on the contents of luteolin and verbascoside（P>0.05），but the content of luteolin and verbascoside was the best when the water addition ratio was 14 times. There was a significant difference in the effect of the number of decoction times（P< 0.05），and the contents of verbascoside and luteolin in the extract was the highest when the number of decoctions was 3 times. The orthogonal test results showed that the extraction times had the greatest influence on the contents of multein and luteolin，followed by the extraction time，the ratio of solid to liquid had the least influence，and the optimal water extraction process was 14 times of water for 3 times，and 1 hour each.

Key words: Callicarpa nudiflora； Water extraction process； Acylate； Mignonette glycosides