关键词: 牛结节性皮肤病； 临床症状； 病理变化； 诊断与防治

Abstract: Lumpy skin disease（LSD），also known as bovine nodular rash or bovine lumpy disease，is a highly infectious class II animal disease that poses a serious harm to the growth and production of cattle. Infected cattles had widespread skin nodules with fever，swollen lymph nodes，edema of the limbs and perineum，yellow secretions from the mouth，nose and eyes，and decreased milk production. The etiology，epidemiology，transmission routes，clinical symptoms，pathological changes，diagnosis，treatment and preventive measures is discussed in this article，and we proposed to strengthen the barn feeding management and made disinfection measures to isolate infected area，to carry out the zap insect ?? borne control work and the surrounding environment to reduce or avoid losses，and proposes to strengthen cattle housing management and disinfection measures，isolate the infected area，and carry out insect vector control in cattle farms and the surrounding environment to improve the prevention and control ability and minimize or avoid losses.

Key words: bovine nodular dermatosis； Clinical symptoms； Pathological changes； Diagnosis and prevention