关键词: 胆汁酸； 胆汁酸受体； 肠道稳态

Abstract: Intestinal barrier is an important basis for animals to maintain homeostasis. Many factors can destroy the integrity of intestinal barrier，leading to bacterial and viral invasion and systemic diseases. Bile acid，as an important component of bile，is synthesized from the liver with cholesterol as raw material and can be discharged into the digestive tract together with bile under the stimulation of exogenous food and related hormones. Bile acids not only emulsify fat，promote intestinal absorption of lipid，regulate liver function，increase energy consumption and other functions，but also play an important role in maintaining intestinal homeostasis. Bile acid receptor are distribution inthe animal internal organs in the body，after bile acid or bile acid analogues activation play a physiological role， and play a role in different organs of mechanism is different，in the intestinal tract，mainly through the bile acid and bile acid receptor and intestinal flora in regulating intestinal steady state，the three interactions，and checks and balances. This review focuses on the roles and mechanisms of bile acids and their receptors in intestinal barrier homeostasis.

Key words: Bile acid； Bile acid receptor； The intestinal steady?state