广东畜牧兽医科技 ›› 2025, Vol. 50 ›› Issue (6): 20-28.DOI: 10.19978/j.cnki.xmsy.2025.06.04

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基孔肯雅热疫情的流行现况、传播机制及防控策略

钱艳红,张翩,陈晶,张晓晓,王晓虎*   

  1. (广东省农业科学院动物卫生研究所,广东省畜禽疫病防治研究重点实验室,农业农村部禽流感等家禽重大疾病防控重点实验室,广东省动物疫病野外科学观测研究站,广东广州510640)
  • 出版日期:2025-12-18 发布日期:2025-12-18
  • 通讯作者: 王晓虎
  • 基金资助:
    广东省现代农业产业技术体系创新团队建设项目(2024CXTD15、2024CXTD15?01);广东省科技计划项目(2023A1111110001);2025年广东省林业科技创新项目;广东省畜禽疫病防治研究重点实验室项目(2023B1212060040);大湾区城市宠物重要疫病血清学调查研究

Epidemic Status, Transmission Mechanism and Prevention and Control Strategies of Chikungunya Fever

QIAN YanhongZHANG PianCHEN JingZHANG XiaoxiaoWANG Xiaohu*   

  1. Institute of Animal Health,Guangdong Academy of Agricultural Sciences / Guangdong Province Key Laboratory of
    Livestock Disease Prevention/Key Laboratory for prevention and control of Avian Influenza and Other Major Poultry
    Diseases,Ministry of Agriculture and Rural Affairs / Guangdong Provincial Observation and Research Station for
    Animal Disease,Guangzhou 510640,China
  • Online:2025-12-18 Published:2025-12-18

摘要: 基孔肯雅热(Chikungunya Fever,CHIKF)是一种由基孔肯雅病毒(Chikungunya vi? rus,CHIKV)引发、经伊蚊传播的急性蚊媒传染病,以发热、皮疹、关节及肌肉疼痛为主要症 状。该病具有明确的流行病学特征和城市传播周期,在人群中具有较高的感染风险。近年 来,病毒遗传变异、全球化进程加快及气候变暖等因素推动了基孔肯雅热的全球传播。迄今为 止,全球已有119个国家和地区报告基孔肯雅热疫情,每年累计病例超过50万例。由于缺乏 获批的商品化疫苗及有效的抗病毒治疗,基孔肯雅热对人类健康、公共卫生体系及社会经济发 展构成了严重威胁。当前,基孔肯雅热在全球范围内的传播态势愈发严峻,尤其是2025年广 东佛山出现的境外输入关联本地传播疫情,进一步凸显了我国防控此类传染病的紧迫性。该 文对全球及国内基孔肯雅热流行现状、输入途径与本土传播特征、传播机制和影响因素,以及综合防控策略等进行了系统梳理,旨在为当前我国科学防控疫情输入与扩散、保障公众健康提 供重要参考。

关键词: 基孔肯雅热, 输入性病例, 本土传播, 传播机制, 防控策略

Abstract: Chikungunya fever is an acute mosquito⁃borne infectious disease caused by the Chikungunya virus(CHIKV) and transmitted primarily by Aedes mosquitoes. The main clinical manifestations include fever,rash,and joint and muscle pain. The disease exhibits distinct epidemiological features and urban transmission cycles,posing a high infection risk to human populations. Factors such as viral genetic mutations,accelerated globalization,and climate warming have driven the global spread of chikungunya fever in recent years. To date,chikungunya outbreaks have been reported in 119 countries and regions,with an estimated annual cumulative case count exceeding 500 000. Due to the absence of approved commercial vaccines or effective antiviral therapies,Chikungunya fever continues to pose a significant threat to human health,public health systems,and socioeconomic development. Currently,the global spread of chikungunya fever is becoming increasingly severe. Notably,the 2025 outbreak in Foshan,Guangdong􀆼linked to imported cases and subsequent local transmission􀆼 has underscored the urgent need for enhanced prevention and control measures in China. This paper systematically reviews the global and domestic epidemiological status of chikungunya fever,its transmission routes and local transmission characteristics,underlying mechanisms and influencing factors,as well as comprehensive prevention and control strategies. The study aims to provide valuable insights for the scientific prevention and control of epidemic importation and spread in China and for safeguarding public health.

Key words: Chikungunya fever, imported cases, local transmission, transmission mechanisms, prevention and control strategies

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